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A neonate with a unique non-Down syndrome transient proliferative megakaryoblastic disease.

Pediatric blood & cancer - 1 Mar 2017

Bertrums Eline J M, Buijs Arjan, van Grotel Martine, Dors Natasja, de Rooij Jasmijn D E, de Haas Valerie, Hopman Sanne, Jongmans Marjolijn C J, Zwaan C M, van den Heuvel-Eibrink Marry M

Abstract excerpt

Transient myeloproliferative disorder (TMD) is a leukemia type that occurs typically in newborns. In Down syndrome, TMD is referred to as transient abnormal myelopoiesis (TAM).32 Recently, transientness has also been reported in acute myeloid leukemia patients with germline trisomy 21 mosaicism, and even in cases with somatic trisomy 21, with or without GATA1 mutations. TMD cases without trisomy 21 are rare, and...

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Identifiers

PMID: 27667142
DOI: 10.1002/pbc.26230

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GATA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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