Article
A cross-sectional observation of the health effects of hydrazine hydrate and differences of its metabolism by NAT2 polymorphism.
International archives of occupational and environmental health - 1 Sept 1998
Nomiyama T, Omae K, Tanaka S, Miyauchi H, Koizumi A, Tsukada M, Wada Y, Mogi T, Imamiya S, Sakurai H
Abstract excerpt
OBJECTIVES: To summarize the results of two studies that attempted to clarify: (1) the health effects of hydrazine hydrate (HH) (N2H4 x H2O: CAS No. 7803-57-8); and (2) the influence of allelic polymorphism of N-acetyltransferase (NAT2) on the metabolism of HH. METHODS: A cross-sectional survey was carried out on 172 male HH-exposed workers and 125 male referent workers at five factories in Japan. The biological...
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