Evidence on N-acetyltransferase allele-associated metabolism of hydrazine in Japanese workers.

doi:10.1097/00043764-199803000-00003

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Article

Evidence on N-acetyltransferase allele-associated metabolism of hydrazine in Japanese workers.

Journal of occupational and environmental medicine - 1 Mar 1998

Koizumi A, Nomiyama T, Tsukada M, Wada Y, Omae K, Tanaka S, Miyauchi H, Imamiya S, Sakurai H

Abstract excerpt

Hydrazine (N2H4), which has been categorized as a weak carcinogen, is a chemical with the one of the largest production rates in Japan. We have investigated the effects of acetylation phenotypes on the metabolism of hydrazine. Genotypes of N-acetyl transferases, NAT2*, were determined using polym...

Topics

Adult
Alleles
Arylamine N-Acetyltransferase
Asian People
Genotype
Humans
Hydrazines
Japan
Male
Middle Aged

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