Susceptibility and outcome in oral cancer: preliminary data showing an association with polymorphism in cytochrome P450 CYP2D6.

doi:10.1097/00008571-199810000-00008

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Article

Susceptibility and outcome in oral cancer: preliminary data showing an association with polymorphism in cytochrome P450 CYP2D6.

Pharmacogenetics - 1 Oct 1998

Worrall S F, Corrigan M, High A, Starr D, Matthias C, Wolf C R, Jones P W, Hand P, Gilford J, Farrell W E, Hoban P, Fryer A A, Strange R C

Abstract excerpt

Members of the cytochrome P450 and glutathione S-transferase supergene families are candidates for susceptibility and outcome in oral squamous cell cancer. We determined GSTM1, GSTM3, GSTT1, CYP1A1 and CYP2D6 genotypes in 100 Caucasian cases and 467 control individuals. The frequency of homozygos...

Topics

Adult
Aged
Aged, 80 and over
Cytochrome P-450 CYP2D6
Disease Susceptibility
Drinking
Female
Genotype
Glutathione Transferase
Heterozygote
Homozygote
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lymph Nodes

Male

Middle Aged

Mouth Neoplasms

Neck

Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 9825835
DOI: 10.1097/00008571-199810000-00008

Genes

GSTM1
GSTM3
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9825835-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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