Article
CYP1A1, CYP2D6, CYP2E1, NAT2, GSTM1 and GSTT1 polymorphisms or their combinations are associated with the increased risk of the laryngeal squamous cell carcinoma.
Mutation research - 1 Jul 2005
Gajecka Marzena, Rydzanicz Malgorzata, Jaskula-Sztul Renata, Kujawski Maciej, Szyfter Witold, Szyfter Krzysztof
Abstract excerpt
Polymorphisms in the selected genes controlling carcinogen metabolism (CYP1A1, CYP2D6, CYP2E1, NAT2, GSTM1, GSTT1) considered separately or in different combinations, were investigated for an association with tobacco smoke-associated squamous cell carcinoma (SCC) of the larynx. The case-control study was performed in 289 patients with laryngeal SCC and in 316 cancer-free controls; all were Caucasian males from...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
