Article
The p53 tumour suppressor gene.
The British journal of surgery - 1 Nov 1998
Steele R J, Thompson A M, Hall P A, Lane D P
Abstract excerpt
BACKGROUND: Abnormalities of the p53 tumour suppressor gene are thought to be central to the development of a high proportion of human tumours. This article reviews current understanding of its function and potential clinical significance. METHODS: Material was identified from previous review art...
Topics
- Apoptosis
- Cell Division
- Gene Expression Regulation, Neoplastic
- Genes, p53
- Genetic Therapy
- Humans
- Mutation
- Neoplasms
- Tumor Suppressor Protein p53