Article
Role of nNOS in blood pressure regulation in eNOS null mutant mice.
Hypertension (Dallas, Tex. : 1979) - 1 Nov 1998
Kurihara N, Alfie M E, Sigmon D H, Rhaleb N E, Shesely E G, Carretero O A
Abstract excerpt
The role of neural nitric oxide synthase (nNOS) in regulating blood pressure (BP) remains uncertain. Recently it was reported that in mice lacking functional endothelial NOS (eNOS) genes (-/-), acute administration of a nonselective NOS inhibitor, Nw-nitro-L-arginine, decreased mean BP, suggestin...
Topics
- Animals
- Blood Pressure
- Cerebellum
- Enzyme Inhibitors
- Heart Rate
- Indazoles
- Mice
- Mice, Inbred C57BL
- Mutation
- NG-Nitroarginine Methyl Ester
- Nitric Oxide Synthase
- Nitric Oxide Synthase Type I
- Nitric Oxide Synthase Type II
- Nitric Oxide Synthase Type III