Role of blocked gap junctional intercellular communication in non-genotoxic carcinogenesis.

doi:10.1016/0378-4274(95)03588-5

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Article

Role of blocked gap junctional intercellular communication in non-genotoxic carcinogenesis.

Toxicology letters - 1 Dec 1995

Mesnil M, Krutovskikh V, Omori Y, Yamasaki H

Abstract excerpt

Gap junctional intercellular communication mediates the transfer of small molecules from the cytoplasm of one cell to that of neighbouring cells. Connexins are the proteins that form the channels responsible for this type of communication. Aberrant expression and function of connexins are often f...

Topics

Animals
Carcinogens
Cell Communication
Connexins
Gap Junctions
Genes, Tumor Suppressor
Humans
Mutation
Neoplasms

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