Article
HLA-DR and -DQ gene polymorphism in Latvian patients with insulin-dependent diabetes mellitus.
Tissue antigens - 1 Oct 1998
Shtauvere A, Rumba I, Dzivite I, Sanjeevi C B
Abstract excerpt
Latvian insulin-dependent diabetes mellitus (IDDM) patients (n=101) and healthy controls (n=111) were analyzed for HLA-DR and DQ polymorphism. DR3-DQ2 and DR4-DQ8 were positively associated and DR15-DQ6, DR13-DQ6, DR1-DQ5 and DQ7 negatively associated with the disease. The incidence of IDDM in La...
Topics
- Adolescent
- Autoantibodies
- Autoantigens
- Biomarkers
- Child
- Child, Preschool
- Diabetes Mellitus, Type 1
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Glutamate Decarboxylase
- HLA-DQ Antigens
- HLA-DR Antigens
- Humans
- Incidence
- Infant
- Latvia
- Membrane Proteins