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Article

HLA-DR and -DQ gene polymorphism in Latvian patients with insulin-dependent diabetes mellitus.

Tissue antigens - 1 Oct 1998

Shtauvere A, Rumba I, Dzivite I, Sanjeevi C B

Abstract excerpt

Latvian insulin-dependent diabetes mellitus (IDDM) patients (n=101) and healthy controls (n=111) were analyzed for HLA-DR and DQ polymorphism. DR3-DQ2 and DR4-DQ8 were positively associated and DR15-DQ6, DR13-DQ6, DR1-DQ5 and DQ7 negatively associated with the disease. The incidence of IDDM in Latvia is very low (6.5 per 100,000) compared to Sweden (24.4 per 100,000), even though Latvia is close to Sweden. The...

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PMID: 9820603
DOI: 10.1111/j.1399-0039.1998.tb03060.x

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