Genomic identification of the minor histocompatibility antigen HA-1 locus by allele-specific PCR.

doi:10.1111/j.1399-0039.1998.tb03053.x

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Article

Genomic identification of the minor histocompatibility antigen HA-1 locus by allele-specific PCR.

Tissue antigens - 1 Oct 1998

Wilke M, Pool J, den Haan J M, Goulmy E

Abstract excerpt

Graft-versus-host disease (GvHD) can be a major complication of allogeneic bone marrow transplantation even in recipients of HLA genotype-identical transplants. Disparities in minor histocompatibility antigens (mHags) between donor and recipient are a potential risk for the development of GvHD. A...

Topics

Adult
Alleles
Base Sequence
Cell Line
Chromosomes, Human, Pair 19
Cosmids
DNA Primers
Graft vs Host Disease
Histocompatibility Testing
Humans
Minor Histocompatibility Antigens
Molecular Sequence Data
Oligopeptides
Polymerase Chain Reaction

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