Genomic typing of minor histocompatibility antigen HA-1 by reference strand mediated conformation analysis (RSCA).

doi:10.1034/j.1399-0039.2000.560109.x

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Article

Genomic typing of minor histocompatibility antigen HA-1 by reference strand mediated conformation analysis (RSCA).

Tissue antigens - 1 Jul 2000

Aróstegui J I, Gallardo D, Rodríguez-Luaces M, Querol S, Madrigal J A, García-López J, Grañena A

Abstract excerpt

Disparities in minor histocompatibility antigen (mHAg) HA-1 are involved in the development of acute graft-versus-host disease (GvHD) in adult recipient after HLA-identical sibling donor hematopoietic stem cell transplantation. The mHAg HA-1 is an HLA-A*0201-restricted nonapeptide, which derives from the cleavage of a protein encoded at chromosome 19. The sequence analysis of HA-1 cDNA identified two alleles,...

Topics

Alleles
DNA Primers
Histocompatibility Testing
Humans
Minor Histocompatibility Antigens
Oligopeptides
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational

Source

Open in PubMed

Identifiers

PMID: 10958358
DOI: 10.1034/j.1399-0039.2000.560109.x

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