Article
Minor histocompatibility antigens as determinants for graft-versus-host disease after allogeneic haematopoietic stem cell transplantation.
International journal of immunogenetics - 1 Dec 2013
Turpeinen H, Ojala P J, Ojala K, Miettinen M, Volin L, Partanen J
Abstract excerpt
Minor histocompatibility antigens (minor H antigens) are genetically polymorphic peptides that have been shown to elicit immune response when mismatched between donor and recipient of haematopoietic stem cell transplantation (HSCT). Depending on the expression profiles, mismatches in these genes may either lead to harmful graft-versus-host (GvH) reaction or desired graft-versus-leukaemia (GvL) effect. We analysed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
