Article
The diallelic locus encoding the minor histocompatibility antigen HA-1 is evolutionarily conserved.
Tissue antigens - 1 Jul 2006
Wieles B, Pool J, Wilke M, Weber M, Kolb H-J, Bontrop R E, Goulmy E
Abstract excerpt
The polymorphic minor histocompatibility antigen HA-1 induces powerful T-cell alloreactivities with important consequences for graft-vs-tumor activity and development of graft-vs-host disease in patients after human leukocyte antigen-matched stem-cell transplantation (SCT). In view of possible translational animal studies, we analyzed the evolutionary conservation of the diallelic HA-1 locus in four mammalian...
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