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Article

Identification of a bipotential precursor cell in hepatic cell lines derived from transgenic mice expressing cyto-Met in the liver.

The Journal of cell biology - 16 Nov 1998

Spagnoli F M, Amicone L, Tripodi M, Weiss M C

Abstract excerpt

Met murine hepatocyte (MMH) lines were established from livers of transgenic mice expressing constitutively active human Met. These lines harbor two cell types: epithelial cells resembling the parental populations and flattened cells with multiple projections and a dispersed growth habit that are designated palmate. Epithelial cells express the liver-enriched transcription factors HNF4 and HNF1alpha, and proteins...

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Identifiers

PMID: 9817765
DOI: 10.1083/jcb.143.4.1101
PMCID: PMC2132947

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