Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

New cellular tools reveal complex epithelial–mesenchymal interactions in hepatocarcinogenesis

1 Jul 2008

Abstract excerpt

To enable detailed analyses of cell interactions in tumour development, new epithelial and mesenchymal cell lines were established from human hepatocellular carcinoma by spontaneous outgrowth in culture. We obtained several hepatocarcinoma (HCC)-, B-lymphoblastoid (BLC)-, and myofibroblastoid (MF)-lines from seven cases. In-depth characterisation included cell kinetics, genotype, tumourigenicity, expression of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Hypoxia, and Metabolism
Share to Fibroblast Growth Factor Research
Share to Liver physiology and pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18594539
DOI: 10.1038/sj.bjc.6604440

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

New cellular tools reveal complex epithelial–mesenchymal interactions in hepatocarcinogenesisPMID 18594539Read ↗

Hepatocellular Carcinomas Originate Predominantly from Hepatocytes and Benign Lesions from Hepatic Progenitor CellsSemantic proximity Read ↗

Identification of a bipotential precursor cell in hepatic cell lines derived from transgenic mice expressing cyto-Met in the liver.Semantic proximity Read ↗

Liver cell lines for the study of hepatocyte functions and immunological responseSemantic proximity Read ↗

Modeling Liver Organogenesis by Recreating Three-Dimensional Collective Cell Migration: A Role for TGFβ PathwaySemantic proximity Read ↗

Establishment and characterization of differentiated, nontransformed hepatocyte cell lines derived from mice transgenic for transforming growth factor alpha.Semantic proximity Read ↗

The role of multipotent cancer associated fibroblasts in hepatocarcinogenesis.Semantic proximity Read ↗

Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulationsSemantic proximity Read ↗

Inducible differentiation and morphogenesis of bipotential liver cell lines from wild-type mouse embryos.Semantic proximity Read ↗

Characterization of biliary epithelial cells isolated from needle biopsies of human liver in the presence of hepatocyte growth factor.Semantic proximity Read ↗

Population expansion, clonal growth, and specific differentiation patterns in primary cultures of hepatocytes induced by HGF/SF, EGF and TGF alpha in a chemically defined (HGM) medium.Semantic proximity Read ↗

Murine hepatocyte cell lines promote expansion and differentiation of NK cells from stem cell precursors.Semantic proximity Read ↗

Inflammatory cytokines promote the retrodifferentiation of tumor-derived hepatocyte-like cells to progenitor cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.