Article
Major histocompatibility complex genotype is associated with disease progression and virus load levels in a cohort of human immunodeficiency virus type 1-infected Caucasians and African Americans.
The Journal of infectious diseases - 1 Dec 1998
Mann D L, Garner R P, Dayhoff D E, Cao K, Fernández-Viña M A, Davis C, Aronson N, Ruiz N, Birx D L, Michael N L
Abstract excerpt
To assess the influence of HLA on AIDS-free survival, human immunodeficiency virus load, and CD4 cell counts, 91 Caucasian and 48 African-American seroprevalent men were typed for HLA classes I and II and TAP alleles. HLA associations with these markers were assessed by assigning sum integer scor...
Topics
- ATP Binding Cassette Transporter, Subfamily B, Member 2
- ATP-Binding Cassette Transporters
- Acquired Immunodeficiency Syndrome
- Black People
- CD4 Lymphocyte Count
- Cohort Studies
- Disease-Free Survival
- Genes, MHC Class I
- Genes, MHC Class II
- Genetic Variation
- Genotype
- HIV Envelope Protein gp160