Article
MHC class I alleles influence set-point viral load and survival time in simian immunodeficiency virus-infected rhesus monkeys.
Journal of immunology (Baltimore, Md. : 1950) - 15 Sept 2002
Mühl Thorsten, Krawczak Michael, Ten Haaft Peter, Hunsmann Gerhard, Sauermann Ulrike
Abstract excerpt
In HIV-infected humans and SIV-infected rhesus macaques, host genes influence viral containment and hence the duration of the disease-free latency period. Our knowledge of the rhesus monkey immunogenetics, however, is limited. In this study, we describe partial cDNA sequences of five newly discovered rhesus macaque (Mamu) class I alleles and PCR-based typing techniques for the novel and previously published Mhc...
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