Article
Sources of NADPH and expression of mammalian NADP+-specific isocitrate dehydrogenases in Saccharomyces cerevisiae.
The Journal of biological chemistry - 20 Nov 1998
Minard K I, Jennings G T, Loftus T M, Xuan D, McAlister-Henn L
Abstract excerpt
To compare roles of specific enzymes in supply of NADPH for cellular biosynthesis, collections of yeast mutants were constructed by gene disruptions and matings. These mutants include haploid strains containing all possible combinations of deletions in yeast genes encoding three differentially co...
Topics
- Animals
- Biological Transport
- Cell Compartmentation
- Gene Expression
- Genes, Fungal
- Genetic Complementation Test
- Glucosephosphate Dehydrogenase
- Isocitrate Dehydrogenase
- Isoenzymes
- Microbodies
- Mitochondria
- Mutation
- NADP
- Pentose Phosphate Pathway
- Reproduction
- Restriction Mapping
- Saccharomyces cerevisiae
- Spores, Fungal