Article
Antioxidant function of cytosolic sources of NADPH in yeast.
Free radical biology & medicine - 15 Sept 2001
Minard K I, McAlister-Henn L
Abstract excerpt
The relative antioxidant functions of thiol-dependent mechanisms and of direct catalytic inactivation of H2O2 were examined using a collection of yeast mutants containing disruptions in single or multiple genes encoding two major enzymatic sources of NADPH [glucose-6-phosphate dehydrogenase (ZWF1) and cytosolic NADP+-specific isocitrate dehydrogenase (IDP2)] and in genes encoding two major cellular peroxidases...
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