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Article

Subunit structure, expression, and function of NAD(H)-specific isocitrate dehydrogenase in Saccharomyces cerevisiae.

Journal of bacteriology - 1 Aug 1990

Keys D A, McAlister-Henn L

Abstract excerpt

Mitochondrial NAD(H)-specific isocitrate dehydrogenase was purified from Saccharomyces cerevisiae for analyses of subunit structure and expression. Two subunits of the enzyme with different molecular weights (39,000 and 40,000) and slightly different isoelectric points were resolved by denaturing electrophoretic techniques. Sequence analysis of the purified subunits showed that the polypeptides have different...

Topics

Chromatography, Gel
Chromatography, Ion Exchange
Gene Expression
Isocitrate Dehydrogenase
Kinetics
Macromolecular Substances
Malate Dehydrogenase
Mitochondria
Molecular Weight
Mutation
Oxygen Consumption

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Saccharomyces cerevisiae

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Open in PubMed Open full text

Identifiers

PMID: 2198251
DOI: 10.1128/jb.172.8.4280-4287.1990
PMCID: PMC213252

Genes

IDH1
IDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2198251-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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