Article
The specification of sympathetic neurotransmitter phenotype depends on gp130 cytokine receptor signaling.
Development (Cambridge, England) - 1 Dec 1998
Geissen M, Heller S, Pennica D, Ernsberger U, Rohrer H
Abstract excerpt
Sympathetic ganglia are composed of noradrenergic and cholinergic neurons. The differentiation of cholinergic sympathetic neurons is characterized by the expression of choline acetyltransferase (ChAT) and vasoactive intestinal peptide (VIP), induced in vitro by a subfamily of cytokines, including...
Topics
- Amino Acid Sequence
- Animals
- Antigens, CD
- Cells, Cultured
- Chick Embryo
- Choline O-Acetyltransferase
- Cytokine Receptor gp130
- Cytokines
- Ganglia, Sympathetic
- Gene Expression Regulation
- Gene Expression Regulation, Developmental
- Humans
- Membrane Glycoproteins
- Molecular Sequence Data
- Neurons
- Phenotype
- RNA, Antisense
- Receptors, Cytokine