Article
GPA and CNTF produce similar effects in sympathetic neurones but differ in receptor binding.
Neuroreport - 13 Dec 1993
Heller S, Huber J, Finn T P, Nishi R, Rohrer H
Abstract excerpt
The effects of growth promoting activity (GPA) on sympathetic neurone development were investigated in vitro and compared with the effects of ciliary neurotrophic factor (CNTF). GPA interfered with sympathetic neurone proliferation and induced the expression of vasoactive intestinal peptide (VIP) in neurones from 7-day-old (E7) chick embryos. The biological effects observed with saturating levels of GPA are...
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