Article
Target determination of neurotransmitter phenotype in sympathetic neurons.
Journal of neurobiology - 1 Jun 1994
Schotzinger R, Yin X, Landis S
Abstract excerpt
While the majority of sympathetic neurons are noradrenergic, a minority population are cholinergic. At least one population of cholinergic sympathetic neurons arises during development by a target-dependent conversion from an initial noradrenergic phenotype. Evidence for retrograde specification has been obtained from transplantation studies in which sympathetic neurons that normally express a noradrenergic...
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