Article
The association of nonsense codons with exon skipping.
Mutation research - 1 Sept 1998
Valentine C R
Abstract excerpt
Some genes that contain premature nonsense codons express alternatively-spliced mRNA that has skipped the exon containing the nonsense codon. This paradoxical association of translation signals (nonsense codons) and RNA splicing has inspired numerous explanations. The first is based on the fact t...
Topics
- Animals
- Cell Nucleus
- Codon, Nonsense
- Codon, Terminator
- Exons
- Humans
- Mutation
- RNA Splicing
- RNA, Messenger
- Reverse Transcriptase Polymerase Chain Reaction
