Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Phenotyping of human glutathione S-transferase hGSTT1-1: a comparison of two ex vivo routine procedures.

Archives of toxicology - 1 Nov 2002

Müller Michael, Bünger Jürgen, Voss Michael, Westphal Götz, Ruhnau Peter, Hallier Ernst

Abstract excerpt

The human glutathione S-transferase hGSTT1-1 is characterized by a polymorphism displaying three phenotypes: the "non-conjugator" (NC) phenotype expresses no or only a residual activity due to a homozygous deletion of the hGSTT1 gene, a medium hGSTT1-1 activity can be demonstrated for the "low conjugator" (LC) phenotype as the heterozygous bearer of one hGSTT1 allele, and a high hGSTT1-1 activity is detected for...

Topics

Join the communities discussing this publication.

Chromatography, High Pressure Liquid
Genotype
Glutathione Transferase
Phenotype

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 12415426
DOI: 10.1007/s00204-002-0391-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotyping of human glutathione S-transferase hGSTT1-1: a comparison of two ex vivo routine procedures.PMID 12415426Read ↗

Inhibition of the human erythrocytic glutathione-S-transferase T1 (GST T1) by thimerosal.Semantic proximity Read ↗

The hereditary transmission of the glutathione transferase hGSTT1-1 conjugator phenotype in a large family.Semantic proximity Read ↗

Comparative genotyping and phenotyping of glutathione S-transferase GSTT1.Semantic proximity Read ↗

Polymorphic distribution of glutathione transferase activity with methyl chloride in human blood.Semantic proximity Read ↗

Glutathione transferase activity and formation of macromolecular adducts in two cases of acute methyl bromide poisoning.Semantic proximity Read ↗

Determination of thiopurine methyltransferase phenotype in isolated human erythrocytes using a new simple nonradioactive HPLC method.Semantic proximity Read ↗

Determination of thiopurine S-methyltransferase (TPMT) activity by comparing various normalization factors: reference values for Estonian population using HPLC-UV assay.Semantic proximity Read ↗

Characterization of the glutathione S-transferase GSTT1 deletion: discrimination of all genotypes by polymerase chain reaction indicates a trimodular genotype-phenotype correlation.Semantic proximity Read ↗

Genotypic and phenotypic determination of polymorphic glutathione transferase T1 in a Swedish population.Semantic proximity Read ↗

Concordance between enzyme activity and genotype of glutathione S-transferase theta (GSTT1).Semantic proximity Read ↗

Thiopurine S-methyltransferase activity in human erythrocytes: a new HPLC method using 6-thioguanine as substrate.Semantic proximity Read ↗

Polymorphism of glutathione S-transferases and susceptibility to acrylonitrile and dimethylsulfate in cases of intoxication.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.