Article
Genetic polymorphisms in the formaldehyde dehydrogenase gene and their biological significance.
Toxicology letters - 30 Nov 2011
Just Walter, Zeller Jasmin, Riegert Clarissa, Speit Günter
Abstract excerpt
The GSH-dependent formaldehyde dehydrogenase (FDH) is the most important enzyme for the metabolic inactivation of formaldehyde. We studied three polymorphisms of this gene with the intention to elucidate their relevance for inter-individual differences in the protection against the (geno-)toxicity of FA. The first polymorphism (rs11568816) was investigated using real-time PCR and restriction fragment analysis in...
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