A long-range restriction map across 3 Mb of the chromosome 11 breakpoint region of a translocation linked to schizophrenia: localization of the breakpoint and the search for neighbouring genes.

doi:10.1097/00041444-199800830-00007

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

A long-range restriction map across 3 Mb of the chromosome 11 breakpoint region of a translocation linked to schizophrenia: localization of the breakpoint and the search for neighbouring genes.

Psychiatric genetics - 1 Jan 1998

Millar J K, Brown J, Maule J C, Shibasaki Y, Christie S, Lawson D, Anderson S, Wilson-Annan J C, Devon R S, St Clair D M, Blackwood D H, Muir W J, Porteous D J

Abstract excerpt

A balanced t(1;11)(q42.1;q14.3) translocation segregates with schizophrenia and related mental illness in a single large Scottish pedigree. We have constructed a long-range restriction map covering at least 3 Mb of the chromosome 11 breakpoint region and conducted searches for genes whose express...

Topics

Cells, Cultured
Chromosomes, Artificial, Yeast
Chromosomes, Human, Pair 1
Chromosomes, Human, Pair 11
Cosmids
CpG Islands
Expressed Sequence Tags
Gene Library
Genetic Predisposition to Disease
Humans
In Situ Hybridization, Fluorescence
Pedigree

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

Restriction Mapping

Schizophrenia

Scotland

Transcription, Genetic

Translocation, Genetic

Source

Open in PubMed

Identifiers

PMID: 9800219
DOI: 10.1097/00041444-199800830-00007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9800219-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.