Article
Novel transcribed sequences neighbouring a translocation breakpoint associated with schizophrenia.
American journal of medical genetics - 21 Feb 1997
Devon R S, Evans K L, Maule J C, Christie S, Anderson S, Brown J, Shibasaki Y, Porteous D J, Brookes A J
Abstract excerpt
A 1.3Mb chromosome 11-specific yeast artificial chromosome (YAC) that spans a t(1;11) translocation breakpoint associated with major psychosis has been used to enrich cDNAs that are encoded within it and expressed in the human foetal brain. Database analysis of the selected fragments led to the i...
Topics
- Chromosomes, Artificial, Yeast
- Chromosomes, Human, Pair 1
- Chromosomes, Human, Pair 11
- DNA Primers
- DNA, Complementary
- Genetic Markers
- Humans
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Schizophrenia
- Translocation, Genetic
- Tubulin