Article
An allelic association study of two polymorphic markers in close proximity to a balanced translocation t(1:11) that co-segregates with mental illness.
Psychiatric genetics - 1 Jan 1997
Wilson-Annan J C, Blackwood D H, Muir W, Millar J K, Porteous D J
Abstract excerpt
We report a case control association study using polymorphic markers D1S1621 and D11S931 in unrelated individuals with schizophrenia, unipolar depression and a matched control group. The two polymorphic markers were identified during the positional cloning of the translocation breakpoint t(1:11)(...
Topics
- Alleles
- Case-Control Studies
- Chromosomes, Human, Pair 1
- Chromosomes, Human, Pair 11
- Data Interpretation, Statistical
- Depression
- Gene Frequency
- Genetic Linkage
- Genetic Markers
- Genotype
- Humans
- Mental Disorders
- Polymorphism, Genetic
- Schizophrenia
- Translocation, Genetic