Article
Genomewide linkage scan of 409 European-ancestry and African American families with schizophrenia: suggestive evidence of linkage at 8p23.3-p21.2 and 11p13.1-q14.1 in the combined sample.
American journal of human genetics - 1 Feb 2006
Suarez Brian K, Duan Jubao, Sanders Alan R, Hinrichs Anthony L, Jin Carol H, Hou Cuiping, Buccola Nancy G, Hale Nancy, Weilbaecher Ann N, Nertney Deborah A, Olincy Ann, Green Susan, Schaffer Arthur W, Smith Christopher J, Hannah Dominique E, Rice John P, Cox Nancy J, Martinez Maria, Mowry Bryan J, Amin Farooq, Silverman Jeremy M, Black Donald W, Byerley William F, Crowe Raymond R, Freedman Robert, Cloninger C Robert, Levinson Douglas F, Gejman Pablo V
Abstract excerpt
We report the clinical characteristics of a schizophrenia sample of 409 pedigrees--263 of European ancestry (EA) and 146 of African American ancestry (AA)--together with the results of a genome scan (with a simple tandem repeat polymorphism interval of 9 cM) and follow-up fine mapping. A family was required to have a proband with schizophrenia (SZ) and one or more siblings of the proband with SZ or...
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