Article
A multimodal attempt to follow-up linkage regions using RNA expression, SNPs and CpG methylation in schizophrenia and bipolar disorder kindreds.
European journal of human genetics : EJHG - 1 Apr 2020
Chagnon Yvon C, Maziade Michel, Paccalet Thomas, Croteau Jordie, Fournier Alain, Roy Marc-André, Bureau Alexandre
Abstract excerpt
The complexity of schizophrenia (SZ) and bipolar disorder (BD) has slowed down progress in understanding their genetic roots. Alternative genomic approaches are needed to bypass these difficulties. We attempted a multimodal approach to follow-up on reported linkage findings in SZ and BD from the Eastern Quebec kindreds in chromosomes 3q21, 4p34, 6p22, 8p21, 8p11, 13q11-q14, 15q13, 16p12, and 18q21. First, in 498...
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