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Article

Serum response factor controls transcriptional network regulating epidermal function and hair follicle morphogenesis.

The Journal of investigative dermatology - 1 Mar 2013

Lin Congxing, Hindes Anna, Burns Carole J, Koppel Aaron C, Kiss Alexi, Yin Yan, Ma Liang, Blumenberg Miroslav, Khnykin Denis, Jahnsen Frode L, Crosby Seth D, Ramanan Narendrakumar, Efimova Tatiana

Abstract excerpt

Serum response factor (SRF) is a transcription factor that regulates the expression of growth-related immediate-early, cytoskeletal, and muscle-specific genes to control growth, differentiation, and cytoskeletal integrity in different cell types. To investigate the role for SRF in epidermal development and homeostasis, we conditionally knocked out SRF in epidermal keratinocytes. We report that SRF deletion...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23151848
DOI: 10.1038/jid.2012.378

Genes

SRF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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