Article
Evaluation of the BeTha gene 1 kit for the qualitative detection of the eight most common Mediterranean beta-thalassemia mutations.
American journal of hematology - 1 Nov 1998
Ugozzoli L A, Lowery J D, Reyes A A, Lin C I, Re A, Locati F, Galanello R, Macioni L, Maggio A, Giambona A, Loutradi A, Boussiou M, Wallace R B
Abstract excerpt
We describe the evaluation of the Bio-Rad BeTha Gene 1 kit (Bio-Rad Laboratories, Hercules, CA), a DNA-probe assay designed for the qualitative determination of the eight most common Mediterranean beta-thalassemia mutations. The kit utilizes the principle of allele-specific oligonucleotide (ASO)...
Topics
- Alleles
- Chorionic Villi Sampling
- DNA
- Enzyme-Linked Immunosorbent Assay
- Evaluation Studies as Topic
- Genotype
- Humans
- In Situ Hybridization
- Mediterranean Region
- Mutation
- Oligonucleotide Probes
- Prenatal Diagnosis
- Reagent Kits, Diagnostic