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Lateral flow dipstick test for genotyping of 15 beta-globin gene (HBB) mutations with naked-eye detection.

Analytica chimica acta - 21 May 2012

Papanikos Frantzeskos, Iliadi Alexandra, Petropoulou Margarita, Ioannou Penelope C, Christopoulos Theodore K, Kanavakis Emmanuel, Traeger-Synodinos Jan

Abstract excerpt

For definitive diagnosis of thalassemia carriers and patients, as well as for prenatal diagnosis, genotype analysis is of fundamental importance. We report a dry-reagent, lateral flow dipstick test that enables visual genotyping (detection by naked eye) of 15 mutations common in Mediterranean populations in the beta-globin gene (HBB). The method comprises 3 simple steps: (i) PCR amplification of a single 1896 bp...

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PMID: 22541824
DOI: 10.1016/j.aca.2012.03.041

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HBB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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