Article
Effect of Rev on the intranuclear localization of HIV-1 unspliced RNA.
Virology - 30 Sept 1998
Favaro J P, Borg K T, Arrigo S J, Schmidt M G
Abstract excerpt
Human immunodeficiency virus type 1 (HIV-1) Rev is a 19-kDa regulatory protein which binds to unspliced and partially spliced HIV-1 RNAs. Export, splicing, stability, and translation of HIV-1 RNAs are influenced by Rev. To further understand the effect of Rev on HIV-1 RNA splicing, the intranuclear localization of unspliced HIV-1 RNA and a cellular splicing factor was examined in the presence and absence of Rev....
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