Effect of Rev on the intranuclear localization of HIV-1 unspliced RNA.

doi:10.1006/viro.1998.9312

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Article

Effect of Rev on the intranuclear localization of HIV-1 unspliced RNA.

Virology - 30 Sept 1998

Favaro J P, Borg K T, Arrigo S J, Schmidt M G

Abstract excerpt

Human immunodeficiency virus type 1 (HIV-1) Rev is a 19-kDa regulatory protein which binds to unspliced and partially spliced HIV-1 RNAs. Export, splicing, stability, and translation of HIV-1 RNAs are influenced by Rev. To further understand the effect of Rev on HIV-1 RNA splicing, the intranucle...

Topics

Cell Line
Cell Nucleus
Gene Products, rev
Genes, rev
HIV-1
Humans
In Situ Hybridization, Fluorescence
Microscopy, Confocal
Mutation
Nuclear Proteins
RNA Splicing
RNA, Viral
Ribonucleoproteins
Serine-Arginine Splicing Factors
Transfection
rev Gene Products, Human Immunodeficiency Virus

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