Article
Detection of DNA abnormalities by arbitrarily primed PCR fingerprinting: allelic losses in chromosome 10q in lung cancers.
Biochemical and biophysical research communications - 9 Oct 1998
Kawakami K, Yasuda J, Shiraishi M, Kayama T, Doi K, Perucho M, Sekiya T
Abstract excerpt
DNA fingerprinting using arbitrarily primed PCR (AP-PCR) is useful for detecting cancer-specific DNA aberrations without targeting any particular genes or knowing any nucleotide sequences in advance. AP-PCR fingerprinting is an efficient method for finding loss of anonymous chromosomal regions in...
Topics
- Alleles
- Carcinoma, Non-Small-Cell Lung
- Chromosome Aberrations
- Chromosome Disorders
- Chromosome Mapping
- Chromosomes, Human, Pair 10
- DNA Fingerprinting
- DNA, Neoplasm
- Humans
- Loss of Heterozygosity
- Lung Neoplasms
- Microsatellite Repeats
- Polymerase Chain Reaction