Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of the NAT1*10 genotype with increased chromosome aberrations and higher lung cancer risk in cigarette smokers.

Mutation research - 26 Feb 1998

Abdel-Rahman S Z, El-Zein R A, Zwischenberger J B, Au W W

Abstract excerpt

The NAT1 gene exhibits polymorphisms in the non-coding polyadenylation region with a number of alleles. Of these alleles, NAT1*10 is responsible for increased NAT1 enzyme levels and is reported to be associated with increased risk for colorectal and bladder cancers. In view of the possible role of the NAT1 gene product in the metabolism of a number of cigarette smoke carcinogens, we tested the possibility that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Chromosome Aberrations
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genotype

Share to Isoenzymes

Share to Polymorphism, Genetic

Share to Risk Factors

Source

Identifiers

PMID: 9626964
DOI: 10.1016/s0027-5107(97)00238-8

Genes

NAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of the NAT1*10 genotype with increased chromosome aberrations and higher lung cancer risk in cigarette smokers.PMID 9626964Read ↗

Functional analysis of arylamine N-acetyltransferase 1 (NAT1) NAT1*10 haplotypes in a complete NATb mRNA construct.Semantic proximity Read ↗

Predisposing genes and increased chromosome aberrations in lung cancer cigarette smokers.Semantic proximity Read ↗

Polymorphism in the N-acetyltransferase 1 (NAT1) polyadenylation signal: association of NAT1*10 allele with higher N-acetylation activity in bladder and colon tissue.Semantic proximity Read ↗

Molecular analysis of the N-acetyltransferase 1 gene (NAT1*) using polymerase chain reaction-restriction fragment-single strand conformation polymorphism assay.Semantic proximity Read ↗

Association of NAT1 and NAT2 polymorphisms to urinary bladder cancer: significantly reduced risk in subjects with NAT1*10.Semantic proximity Read ↗

Single-track sequencing for genotyping of multiple SNPs in the N-acetyltransferase 1 (NAT1) gene.Semantic proximity Read ↗

NATb/NAT1*4 promotes greater arylamine N-acetyltransferase 1 mediated DNA adducts and mutations than NATa/NAT1*4 following exposure to 4-aminobiphenyl.Semantic proximity Read ↗

A restriction fragment length polymorphism assay that differentiates human N-acetyltransferase-1 (NAT1) alleles.Semantic proximity Read ↗

Polymorphism in the N-acetyltransferase 1 alleles NAT1*10 and NAT1*14A and cytological gradings of exfoliated urothelial cells in benzidine-exposed Chinese workers: discussion of ethnic differences.Semantic proximity Read ↗

Real-time PCR analysis of the N-acetyltransferase NAT1 allele *3, *4, *10, *11, *14 and *17 polymorphism in squamous cell cancer of head and neck.Semantic proximity Read ↗

Relationship between NAT1 genotype and phenotype in a Japanese population.Semantic proximity Read ↗

Arylamine N-acetyltransferase type 2 (NAT2), chromosome 8 aneuploidy, and identification of a novel NAT1 cosmid clone: an investigation in bladder cancer by interphase FISH.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.