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Article

Molecular alterations at 9q33.1 and polyploidy in asbestos-related lung cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jan 2009

Nymark Penny, Kettunen Eeva, Aavikko Mervi, Ruosaari Salla, Kuosma Eeva, Vanhala Esa, Salmenkivi Kaisa, Pirinen Risto, Karjalainen Antti, Knuutila Sakari, Wikman Harriet, Anttila Sisko

Abstract excerpt

PURPOSE: Asbestos causes DNA damage and the fibers, together with tobacco smoke, have a synergistic effect on lung cancer risk. We recently identified 18 chromosomal regions that showed differences in DNA copy number between the lung tumors of asbestos-exposed and nonexposed patients. One of the previously identified asbestos-associated chromosomal regions at 9q was further analyzed for allelic imbalance and DNA...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosomes, Artificial, Bacterial

Share to Chromosomes, Human, Pair 9

Share to Gene Expression Regulation, Neoplastic

Share to In Situ Hybridization, Fluorescence

Share to Lung Neoplasms

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Source

Identifiers

PMID: 19147751
DOI: 10.1158/1078-0432.CCR-08-1852

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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