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Article

Evidence for oligogenic inheritance of type 1 diabetes in a large Bedouin Arab family.

The Journal of clinical investigation - 15 Oct 1998

Verge C F, Vardi P, Babu S, Bao F, Erlich H A, Bugawan T, Tiosano D, Yu L, Eisenbarth G S, Fain P R

Abstract excerpt

Based on a genomic search for linkage, a locus contributing to type 1 diabetes in a large Bedouin Arab family (19 affected relatives) maps to the long arm of chromosome 10 (10q25; nonparametric linkage = 4.99; P = 0.00004). All affected relatives carry one or two high-risk HLA-DR3 haplotypes that are rarely found in other family members. One chromosome 10 haplotype, the B haplotype, was transmitted from a...

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Identifiers

PMID: 9788970
DOI: 10.1172/JCI3379
PMCID: PMC509007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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