Article
Evidence for a type 1 diabetes susceptibility locus (IDDM10) on human chromosome 10p11-q11.
Human molecular genetics - 1 Jul 1997
Reed P, Cucca F, Jenkins S, Merriman M, Wilson A, McKinney P, Bosi E, Joner G, Rønningen K S, Rønningen K, Thorsby E, Undlien D, Merriman T, Barnett A, Bain S, Todd J
Abstract excerpt
A region of linkage to type 1 diabetes has been defined on human chromosome 10p11-q11 (IDDM10; P = 0.0007) using 236 UK and 76 US affected sibpairs and a 1 cM resolution microsatellite marker map. Analysis by the transmission disequilibrium test (TDT) in 1159 families with at least one diabetic c...
Topics
- Adolescent
- Chromosome Mapping
- Chromosomes, Human, Pair 10
- Diabetes Mellitus, Type 1
- Genetic Linkage
- Genetic Markers
- Genetic Predisposition to Disease
- Humans
- Italy
- Microsatellite Repeats
- Norway
