Article
Evidence for a type 1 diabetes susceptibility locus (IDDM10) on human chromosome 10p11-q11.
Human molecular genetics - 1 Jul 1997
Reed P, Cucca F, Jenkins S, Merriman M, Wilson A, McKinney P, Bosi E, Joner G, Rønningen K S, Rønningen K, Thorsby E, Undlien D, Merriman T, Barnett A, Bain S, Todd J
Abstract excerpt
A region of linkage to type 1 diabetes has been defined on human chromosome 10p11-q11 (IDDM10; P = 0.0007) using 236 UK and 76 US affected sibpairs and a 1 cM resolution microsatellite marker map. Analysis by the transmission disequilibrium test (TDT) in 1159 families with at least one diabetic child, from the UK, the US, Norway, Sardinia and Italy provided additional support for linkage at D10S193 (P = 0.006, Pc...
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