Article
HLA DQA1-DQB1 genotypes in Bedouin families with celiac disease.
Human immunology - 1 Jun 2002
Neuhausen Susan L, Weizman Zvi, Camp Nicola J, Elbedour Khalil, Sheffield Val C, Zone John J, Carmi Rivka
Abstract excerpt
Celiac disease (CD) has a strong genetic association with human leukocyte antigens (HLA). The primary susceptibility for CD is HLA-DQA1*05 DQB1*02 (also known as DQ2), with the remainder of cases primarily HLA-DQA1*03 DQB1*03 (also known as DQ8). In a set of nine Bedouin multiplex celiac disease families and one simplex, we genotyped DNA samples at HLA DQA1 and DQB1. Nineteen celiac disease patients had at least...
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