Article
Searching for type 2 diabetes genes on chromosome 20.
Diabetes - 1 Dec 2002
Permutt Marshall Alan, Wasson Jonathan, Love-Gregory Latisha, Ma Jiyan, Skolnick Gary, Suarez Brian, Lin Jennifer, Glaser Benjamin
Abstract excerpt
Genome scans in families with type 2 diabetes identified a putative locus on chromosome 20q. For this study, linkage disequilibrium mapping was used in an effort to narrow a 7.3-Mb region in an Ashkenazi type 2 diabetic population. The region encompassed a 1-logarithm of odds (LOD) interval around the microsatellite marker D20S107, which gave a LOD score of >3 in linkage analysis of a combined Caucasian...
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