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Article

Retinoid absorption and storage is impaired in mice lacking lecithin:retinol acyltransferase (LRAT).

The Journal of biological chemistry - 21 Oct 2005

O'Byrne Sheila M, Wongsiriroj Nuttaporn, Libien Jenny, Vogel Silke, Goldberg Ira J, Baehr Wolfgang, Palczewski Krzysztof, Blaner William S

Abstract excerpt

Lecithin:retinol acyltransferase (LRAT) is believed to be the predominant if not the sole enzyme in the body responsible for the physiologic esterification of retinol. We have studied Lrat-deficient (Lrat-/-) mice to gain a better understanding of how these mice take up and store dietary retinoids and to determine whether other enzymes may be responsible for retinol esterification in the body. Although the...

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Identifiers

PMID: 16115871
DOI: 10.1074/jbc.M507924200
PMCID: PMC1352312

Genes

LRAT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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