Article
Distribution of glutathione S-transferase T1 and M1 genes polymorphisms in North East Indians: a potential report.
Genetic testing and molecular biomarkers - 1 Apr 2010
Thoudam Regina Devi, Yadav Dhirendra Singh, Mishra Ashwani Kumar, Kaushal Mishi, Ihsan Rakhshan, Chattopadhyay Indranil, Chauhan Pradeep Singh, Sarma Jagannath, Zomawia Eric, Verma Yogesh, Nandkumar A, Mahanta Jagadish, Phukan Rupkumar, Kapur Sujala, Saxena Sunita
Abstract excerpt
BACKGROUND: Detoxifying glutathione S-transferase (GST) gene polymorphisms show variation in different ethnic populations. GST detoxifies and metabolizes carcinogens, including oxygen free radicals. GST polymorphisms have been associated with susceptibility to different diseases. In the current study, allelic polymorphisms of GSTM1 and GSTT1 were analyzed in three ethnic groups of North East (NE) India where a...
Topics
Join the communities discussing this publication.