Article
Glutathione S-transferase M1 and T1 polymorphisms in Brazilian African descendants.
Human biology - 1 Feb 2007
Hiragi Cássia de Oliveira, de Oliveira Silviene Fabiana, Hatagima Ana, Ferreira Luzitano Brandão, Grisolia Cesar Koppe, Klautau-Guimarães Maria de Nazaré
Abstract excerpt
The glutathione S-transferase gene family has an important role in the biotransformation and detoxification of different xenobiotics and endogenous compounds. Two polymorphic genes of this family, GSTM1 and GSTT1, present null alleles that consequently do not produce the respective enzyme when the genotype is homozygous. These polymorphisms are also interesting for population dynamics studies because they have...
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