Apolipoprotein E polymorphism influences the cerebral metabolic pattern in Alzheimer's disease.

doi:10.1016/s0304-3940(98)00673-9

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Article

Apolipoprotein E polymorphism influences the cerebral metabolic pattern in Alzheimer's disease.

Neuroscience letters - 18 Sept 1998

Mielke R, Zerres K, Uhlhaas S, Kessler J, Heiss W D

Abstract excerpt

In 49 patients with the clinical diagnosis of probable Alzheimer's disease (AD) apoE genotyping as well as regional cerebral glucose metabolism (rCMRGI) using positron emission tomography (PET) of [18F]2-fluoro-2-deoxy-D-glucose (FDG) were studied. The metabolic pattern was condensed to a ratio b...

Topics

Age Factors
Age of Onset
Aged
Aged, 80 and over
Alleles
Alzheimer Disease
Apolipoprotein E4
Apolipoproteins E
Basal Ganglia
Brain Stem
Cerebellum
Cerebral Cortex
DNA
Dementia
Female
Fluorine Radioisotopes
Fluorodeoxyglucose F18
Frontal Lobe

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