Article
Apolipoprotein E polymorphism influences the cerebral metabolic pattern in Alzheimer's disease.
Neuroscience letters - 18 Sept 1998
Mielke R, Zerres K, Uhlhaas S, Kessler J, Heiss W D
Abstract excerpt
In 49 patients with the clinical diagnosis of probable Alzheimer's disease (AD) apoE genotyping as well as regional cerebral glucose metabolism (rCMRGI) using positron emission tomography (PET) of [18F]2-fluoro-2-deoxy-D-glucose (FDG) were studied. The metabolic pattern was condensed to a ratio by dividing the rCMRGI of typically affected regions (temporo-parietal and frontal association cortex) by the rCMRGI of...
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