Article
Functional correlates of Apolipoprotein E genotype in Frontotemporal Lobar Degeneration.
BMC neurology - 24 Aug 2006
Borroni Barbara, Perani Daniela, Archetti Silvana, Agosti Chiara, Paghera Barbara, Bellelli Giuseppe, Di Luca Monica, Padovani Alessandro
Abstract excerpt
BACKGROUND: It has been recently demonstrated that in Frontotemporal Lobar Degeneration (FTLD) memory deficits at presentation are commoner than previously thought. Apolipoprotein E (ApoE) genotype, the major genetic risk factor in sporadic late-onset Alzheimer Disease (AD), modulates cerebral perfusion in late middle-age cognitively normal subjects. ApoE epsilon4 homozygous have reduced glucose metabolism in the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
