Article
Cell Cycle-Regulated Expression of Mammalian <i>CDC6</i> Is Dependent on E2F
1 Nov 1998
Abstract excerpt
The E2F transcription factors are essential regulators of cell growth in multicellular organisms, controlling the expression of a number of genes whose products are involved in DNA replication and cell proliferation. In Saccharomyces cerevisiae, the MBF and SBF transcription complexes have functions similar to those of E2F proteins in higher eukaryotes, by regulating the timed expression of genes implicated in...
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