Article
The Schizosaccharomyces pombe MBF complex requires heterodimerization for entry into S phase.
Molecular and cellular biology - 1 May 1995
Ayté J, Leis J F, Herrera A, Tang E, Yang H, DeCaprio J A
Abstract excerpt
In Schizosaccharomyces pombe, MBF is a DNA-binding complex suspected to activate the transcription of genes necessary for entry into S phase. The MBF complex contains both p85cdc10 and p72res1/sct1. To obtain a better understanding of how the MBF complex regulates gene expression at the G1/S transition, we have performed a genetic analysis of p72res1. We determined that p72res1 can bind specifically to the cdc22...
Topics
- Base Sequence
- Binding Sites
- Cell Cycle Proteins
- DNA Primers
- DNA, Fungal
- DNA-Binding Proteins
- Fungal Proteins
- Molecular Sequence Data
- Mutation
- Protein Conformation
- S Phase