Article
Control of DNA synthesis genes in fission yeast by the cell-cycle gene cdc10+.
Nature - 30 Jan 1992
Lowndes N F, McInerny C J, Johnson A L, Fantes P A, Johnston L H
Abstract excerpt
In the budding yeast Saccharomyces cerevisiae, cell-cycle control over DNA synthesis occurs partly through the coordinate expression in late G1 phase of many, if not all, of the genes required for DNA synthesis. A cis-acting hexamer element ACGCGT (an MluI restriction site) is responsible for coordinating transcriptional regulation of these genes at the G1/S phase boundary and we have identified a binding...
Topics
- Alleles
- Base Sequence
- Cell Cycle
- DNA Replication
- DNA, Fungal
- Fungal Proteins
- Genes, Fungal
- Molecular Sequence Data
- Mutagenesis
- Oligodeoxyribonucleotides
- Plasmids
- Polymerase Chain Reaction